An Interview with Janine Knizia, Haute Regenerative Skincare Founder
Janine Knizia is not just a skincare founder; she is a visionary whose journey through holistic health, and beauty has reshaped how we think about skincare and longevity. With an impressive career, Janine has made an indelible mark on the beauty industry.
As the founder of Janine Knizia Haute Regenerative Skincare, she’s set out to redefine luxury skincare by combining cutting-edge science with ancient plant wisdom. It’s a philosophy that’s not just about enhancing the outer appearance, but about fostering wellness and longevity from within.
Janine’s formulations are not your average beauty products. They represent years of research, countless hours spent perfecting each blend, and an uncompromising commitment to high-vibrational ingredients. With a deep understanding of both ingredient science and the powerful benefits of plants, she scours the globe for the rarest, most potent botanicals - those that can nourish skin at a cellular level. Each product is the result of a meticulous process, one that often involves working alongside labs, scientists, and alchemists to ensure that every formula is not only effective but truly regenerative.
Her commitment to sustainability and efficacy is at the heart of the brand, with an emphasis on harnessing the power of nature to slow the signs of aging and promote healthier skin. After all, Janine believes in more than just surface beauty; she's on a mission to elevate the concept of longevity, combining skincare with nutrition, mindfulness, and epigenetics to offer a holistic approach to aging gracefully.
In this exclusive interview, we dive into Janine’s remarkable journey, her thoughts on the future of skincare, and why her decision to bring Janine Knizia Haute Regenerative Skincare from Paris to London felt like a natural next step. We also explore why she chose to align with Pfeffer Sal for her UK debut, a sanctuary that shares her vision of merging scientific luxury with deep holistic wellness.
What drew you to our clinic? Why did partnering with Pfeffer Sal feel like the right fit for your launch?
From the very beginning, what drew me to Pfeffer Sal was the clinic’s deep-rooted commitment to holistic, but results-driven care.
There’s a warmth and integrity in your work – not just with clients, but in how you approach skincare as a whole. Partnering with Pfeffer Sal felt incredibly natural for my launch because our philosophies are so aligned: groundbreaking innovations, uncompromising quality, and a genuine passion for changing the world of beauty.
Launching in London with such a trusted, forward-thinking clinic feels like the perfect foundation for what’s to come.
Can you tell us a little bit about your journey into skincare and what inspired you to create Janine Knizia?
My journey into skincare began with a deep-rooted passion for holistic health and a lifelong love for the plant kingdom. From a young age, I was captivated by nature’s intelligence and its profound ability to support and heal the body - an early fascination that evolved into a lifelong calling. After becoming a certified holistic health practitioner through the Institute of Integrative Nutrition in New York, I was inspired to create something truly meaningful in the beauty space. In 2017, I launched Europe’s first Clean Beauty Showroom and Agency in Paris, helping to redefine industry standards and bring luxury botanical remedies to the forefront of the European market.
Janine Knizia Skincare was born from a desire to go beyond the surface - to create skincare that doesn’t just care for the skin, but actively transforms it. The mission is to biohack the skin’s aging process at the genetic level, reactivating mature skin cells to perform with the vitality of younger ones. My brand is driven by the superior principles of Nature’s Grandeur, elevated through groundbreaking scientific innovation, advanced with state-of-the-art biotechnology, and empowered by Chronobiology.
Shortcuts were never taken in the relentless pursuit of superior formulations and visible results. With an exceptional depth of knowledge in ingredient science and a global perspective on healing traditions, I continue to seek out the rarest botanicals, the latest breakthroughs, and the most effective ways to support skin health at a cellular and genetic level. This line is a reflection of that commitment- a fusion of nature, science, and soul, designed to support true skin longevity and transformation. And I'm sure anyone has ever experienced such a mind-blowing skin transformation in just 28 days, just to begin.
What's the philosophy behind your brand? What makes it stand out in a crowded skincare world?
The philosophy behind Janine Knizia Skincare is centered around one core belief: that the skin has the innate intelligence to heal, regenerate, and thrive - when supported with the right ingredients, concentrations, formulations and tools.
We don’t chase trends or superficial fixes. Instead, my approach is rooted in skin longevity, science-backed formulation, and a profound respect for nature’s healing power. It’s about nurturing the skin from the inside out and addressing aging at its source - on a cellular and even genetic level. What truly sets us apart in a crowded skincare landscape is our uncompromising commitment to performance and purity. We merge the very best of Nature, working with the most powerful bioidentical Exosomes, or even an exosomal delivery system, while always merging the latest advances in biotechnology and Chronobiology, applying deep ingredient knowledge, holistic wisdom, and high science to every formula.
The result is Haute Regenerative Skincare - a category of its own, where visible transformation meets deep cellular support. In the beginning, it all started with a personal decision because ‘I just thought, I’m going to make my own products, exclusively for myself, using the most resilient nutrient-rich botanicals and potent anti-aging, skin-communicating ingredients at the highest concentrations. Drawing on time-honoured traditions and next-generation science, cost was no object - this was purely a pursuit of excellence for my own skin. That pursuit of excellence became a mission: to share these formulations with other women who demand so much more from their skincare.
Your formulas are incredibly considered. Could you walk us through one hero product and why you created it the way you did?
Every single product in the Janine Knizia Skincare line is a hero product - because I don’t believe in filler formulas or secondary steps. Each one was meticulously created to deliver targeted, high-performance results and work synergistically to biohack the skin’s aging process at the deepest level.
That’s why I developed five transformational core products, each designed to activate a specific phase in the skin’s renewal cycle - supporting everything from cellular regeneration and mitochondrial function to telomere recovery and DNA repair. I don't have a cleanser or a mist by now and I’m sure everyone knows why! I wanted to create a streamlined biohacking ritual with no compromises - where every formula is deeply functional, multi-corrective, and infused with the most resilient botanicals and scientifically advanced actives at optimal concentrations.
These products aren’t just steps in a routine - they are tools for transformation, rooted in the fusion of ancient wisdom and cutting-edge science. Each one exists because it had to - nothing less than extraordinary would do.
How do you go about selecting ingredients - are there any you’re absolutely obsessed with right now?
Selecting the ingredients for my skincare line is a meticulous process rooted in both scientific innovation and a profound respect for nature's intelligence.
Each component is chosen not only for its proven efficacy but also for its ability to synergise with others, creating formulations that truly transform the skin.One ingredient I'm particularly captivated by is RejuveNAD™, a groundbreaking longevity molecule designed to boost NAD⁺ levels within the skin. NAD⁺ is essential for cellular energy and DNA repair, but its levels decline with age. By stimulating the enzyme NAMPT, RejuveNAD™ promotes the endogenous regeneration of NAD⁺, revitalising mitochondrial function and supporting skin rejuvenation at a cellular level.
Another standout is Bio-Identical Exosomes derived from encapsulated grapefruit and watermelon. These plant-based extracellular vesicles mimic human exosomes, facilitating intercellular communication to stimulate glycolysis in dermal fibroblasts. This process enhances cellular energy, boosts mitochondrial function, and significantly reduces senescent cells, often referred to as "zombie cells."
Additionally, the Biotechnological Marine Fermented Microorganism sourced from the sea breeze near Tonga is remarkable. It regulates SP and cortisol release, preventing cellular aging by protecting telomere length. This not only de-stresses the skin but also restores epidermal and dermal balance, leading to visibly younger, firmer, and more hydrated skin.
What was the biggest challenge in formulating your range, and what part of the process surprised you most?
The biggest challenge in formulating my range was, without a doubt, finding a lab willing-and able-to bring my vision to life. I approached multiple formulation labs around the world, but I was consistently told the line was too complex, too ambitious, and too advanced to execute. The level of actives I demanded, the precision of the delivery systems, the synergy of biotech ingredients with nutrient-dense botanicals - it was beyond what most were used to doing.
But I wasn’t willing to compromise. I knew exactly what I wanted: skincare that could truly biohack the skin at a genetic level, and nothing less. So I kept searching until I found the right scientific partners who not only shared my passion for excellence but also had the expertise and vision to make it happen.
What surprised me most was how long the process took - years of research, countless reformulations, and intense testing. But in the end, it was worth every moment.
The formulas are uncompromising, multi-dimensional, and built to perform. It was never about convenience - it was always about creating something that didn’t exist yet.
In your experience, what are some skincare habits people often get wrong - and what would you suggest instead?
One of the biggest issues I see is that people are completely overwhelmed by the skincare industry - constantly bombarded with marketing claims, miracle promises, and aggressive advertising campaigns especially from big brands. It creates so much confusion and disconnects people from what their skin actually needs. There’s a tendency to chase trends and margins instead of results, and to rely on clever branding rather than scientific integrity and innovation and research.
The truth is, great skin doesn’t come from marketing, trends and hypes. It comes from deeply understanding your skin’s biology and your skin needs, using advanced ingredients that are clinically proven to make a real difference, and following a consistent ritual that supports long-term skin health and longevity.
If your brand had a personality, how would you describe it in 3 words?
Visionary. Disruptive. Pioneering.
It’s here to challenge outdated beauty standards, break through industry noise, and push the boundaries of what's possible in skincare - combining next-gen science with nature's most powerful intelligence to truly change the way we approach skin longevity.
What's your own daily skincare routine like? Any non-negotiables?
My daily skincare routine is a deeply intuitive ritual - it's not just about applying products, but about truly connecting with my skin. I always start my day by observing my skin in the mirror, touching it gently, and speaking to it - tuning into its needs and energy. The skin tells a story every day, and I believe in listening closely.
I'm a big advocate for layering, because when done thoughtfully, it allows each product to penetrate deeper and perform at its full potential. I start with my signature essence to flood the skin with hydration and prime it for what comes next. Then I follow with targeted serums and actives, each designed to biohack a specific function - whether it's cellular energy, DNA repair, or barrier support. I always seal everything in with a rich yet breathable moisturiser and, of course, sun protection.
My non-negotiables? High-performance actives as used in my skincare line and daily lymphatic stimulation. Honestly, because of my profession, I’ve tried thousands of products over the past decades.
But the truth is - I can’t go a single day without using every single one of my own formulations. That’s not just because I created them, but because I’ve never experienced anything that makes my skin feel and perform the way these do. It might sound a little intense, but once you start using the products, you feel the difference and you'll look younger day by day. I can’t imagine my routine without them - they’ve become an essential part of who I am and how I want to look.
How should clients incorporate your range into an existing routine and can it play nicely with other brands?
You can absolutely incorporate Janine Knizia Skincare into your existing routine - whether you're fully committed to your current products or just starting to explore new options.
I made sure that every formula in the line is designed to layer beautifully and never pill, no matter what you pair it with. That was non-negotiable for me during development. Whether you're integrating just one product or the full ritual, the line is incredibly versatile and plays well with other brands. The textures are refined, the absorption is seamless, and the actives are intelligently formulated to support, not disrupt the rest of your routine.
It's skincare that adapts to you, while quietly elevating everything else you’re already using.
What's your favourite part of running your own skincare line - creative control, the science, the feedback?
Honestly, my favourite part of running my own skincare line is finally knowing, with full confidence, that I have the right products to stay forever young. I’m a total control freak, and creating this line has allowed me to take control over the aging, or rather, non-aging process in a way I never could before.
Sometimes I couldn’t believe what I was hearing behind the scenes from top labs, formulators and doctors - the compromises, the shortcuts, the lack of integrity in so many formulations out there. That only fuelled my commitment to do things differently, it became an obsession over the years - especially knowing that I'm turning 40 and the time is running. Now, every product is created on my terms: no dilution, no cutting corners, just maximum performance and mind-blowing results. It’s incredibly fulfilling to know I’m not just creating skincare, I’m creating real change in this industry.
Can you walk us through what’s involved in the Janine Knizia Haute Performance Facial? And what do you hope people feel after their first experience with it?
The Janine Knizia Haute Performance Facial is so much more than a treatment - it’s a full-spectrum experience designed to deliver a visible, lasting transformation. I’m unbelievably picky when it comes to facials and treatments in general. I don’t want to leave a treatment room glowing just for a few hours - I want to see a change that lasts for days, weeks, even months. That’s the standard I hold for my own skin, and it’s exactly what I’ve built into this experience.
What makes this facial truly unique is the precision and intention behind every single step. It combines deep, sculpting massage techniques that give the muscles a real workout - lifting, toning, and releasing tension, while also calming the nervous system. It’s equal parts high-performance skin rejuvenation and a deeply restorative experience.
I believe skin reflects how we feel on the inside, so resetting the body and mind is just as important as the visible results. My ultimate commitment is this: everyone who leaves a JK facial should feel like years have been erased from their skin, but also like a weight has been lifted, to feel lighter, happier, more vibrant. It's not just about looking better; it's about feeling fully recharged from the inside out.
THE DESTINATION FOR SKIN HEALTH
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